Focus on "the long tail" - This refers to the portions of the population/market bell curve that reflect smaller markets.
The tail can be very long - lots of potential users who are not being serviced by the organizations that service the core consumers.
Through mass marketing, organizations focus on the center of the bell: That's where the majority of the people are.
With so many people on the Internet it has become much easier to market to people in the tails of the curve.
Specifically, there can be lots of people who are geographically dispersed with a like interest, but who are not interested in what the majority wants.
These people's interests fall into niches for which it was not economical to have service providers except in the largest population centers.